In moments of boredom or concern, seeing how beautiful the structures of nature are can reassure and inspire! I went back to my favourite molecules and selected some protein structures to bring some dynamism and creativity in our SHOP. Have a look at the NEW items with this protein!
This crystal structure belongs to the Crystal Structure of the Lumenal Domain of Calnexin that is a protein with a very long appendage… like a ball on the leash!
It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. Calnexin is a chaperone, meaning that its job is to assist protein to reach their correct folding and ensure quality control. It specifically acts to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum (read more at Wikipedia and DOI: 10.1016/s1097-2765(01)00318-5)