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4q9c: Creativity in the SHOP

In moments of boredom or concern, seeing how beautiful the structures of nature are can reassure and inspire! I went back to my favourite molecules and selected some protein structures to bring some dynamism and creativity in our SHOP. Have a look at the NEW items with this protein!

This crystal structure belongs to the IgNAR antibody domain C3… a protein from shark! what else can I say?

IgNAR antibody domain C3

Sharks have smaller antibodies than usual. IgNAR shows significant structural differences to other antibodies. It has five constant domains (CH) per chain instead of the usual three, several disulfide bonds in unusual positions, and the complementarity-determining region 3 (CDR3) forms an extended loop covering the site which binds to a light chain in other antibodies. These differences, in combination with the phylogenetic age of the cartilaginous fishes, have led to the hypothesis that IgNAR could be more closely related to a primordial antigen-binding protein than the mammalian immunoglobulins. Non-vertebrates do not have antibodies at all. (read more DOI: 10.1073/pnas.1321502111 and Wikipedia)

2w9p: Creativity in the SHOP

In moments of boredom or concern, seeing how beautiful the structures of nature are can reassure and inspire! I went back to my favourite molecules and selected some protein structures to bring some dynamism and creativity in our SHOP. Have a look at the NEW items with this protein!

This crystal structure belongs to the potato multicystatin … such a surprising vegetable.

Potato Multicystatin

Potato (Solanum tuberosum) multicystatin an inhibitor of protease of the family Cys protease and found in the subphellogen layer of potato tubers. In contrast with cystatins from other plant and animal sources, this protein has a high molecular mass of 85 kDa/monomer, compared to 8 or 25 kDa. It can also bind and inhibit several Cys proteases (e.g., papain) simultaneously, and the term multicystatin thus refers to its multiple inhibitory domains (read more DOI: 10.1105/tpc.108.064717 and doi: 10.1105/tpc.108.064717)

Rainy Monday, smiley Monday

Rain keeps me anchored,
Lazy in lockdown and fearful in life
But my imagination travels wild.
My face sighs and demands fresh humid air.
I leave the comfort
And a friend lits a spark
In my mental algorithms and my future.
She knows how
To feed my mind and the Ambition
That on Mondays
Wakes up hungry and angry.
Little monster of mine,
I love you.

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