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4cpa: Creativity in the SHOP

In moments of boredom or concern, seeing how beautiful the structures of nature are can reassure and inspire! I went back to my favourite molecules and selected some protein structures to bring some dynamism and creativity in our SHOP. Have a look at the NEW items with this protein!

This crystal structure belongs to the POTATO CARBOXYPEPTIDASE … one of the nemesis of proteins, argh!!

REFINED CRYSTAL STRUCTURE OF THE POTATO INHIBITOR COMPLEX OF CARBOXYPEPTIDASE A AT 2.5 ANGSTROMS RESOLUTION

A carboxypeptidase is a protease enzyme that hydrolyzes (cleaves) a peptide bond at the carboxy-terminal (C-terminal) end of a protein or peptide. This is in contrast to an aminopeptidases, which cleave peptide bonds at the N-terminus of proteins. Humans, animals, bacteria and plants contain several types of carboxypeptidases that have diverse functions ranging from catabolism to protein maturation.(read more DOI: 10.1038/nature06956 and Wikipedia)

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3cl0: Creativity in the SHOP

In moments of boredom or concern, seeing how beautiful the structures of nature are can reassure and inspire! I went back to my favourite molecules and selected some protein structures to bring some dynamism and creativity in our SHOP. Have a look at the NEW items with this protein!

This crystal structure belongs to the Neuraminidase such a surprising vegetable.

N1 Neuraminidase H274Y + oseltamivir

Neuraminidase is a key protein of influenza viruses and in this structure one inhibitor is also present bound to it. The best-known neuraminidase is the viral neuraminidase, a drug target for the prevention of the spread of influenza infection. The viral neuraminidases are frequently used as antigenic determinants found on the surface of the influenza virus. Some variants of the influenza neuraminidase confer more virulence to the virus than others. The study of neuraminidases and how they evolve, and the research of novel inhibitors are key for having antiviral drugs in the future (read more DOI: 10.1038/nature06956 and Wikipedia)

Open for submission

I am so happy you are snooping in the blog! Are you also writing some short poems and fascinated by science?

How about submitting your work to POETRY FROM THE LAB? Just click below or follow this link for further info.

2w9p: Creativity in the SHOP

In moments of boredom or concern, seeing how beautiful the structures of nature are can reassure and inspire! I went back to my favourite molecules and selected some protein structures to bring some dynamism and creativity in our SHOP. Have a look at the NEW items with this protein!

This crystal structure belongs to the potato multicystatin … such a surprising vegetable.

Potato Multicystatin

Potato (Solanum tuberosum) multicystatin an inhibitor of protease of the family Cys protease and found in the subphellogen layer of potato tubers. In contrast with cystatins from other plant and animal sources, this protein has a high molecular mass of 85 kDa/monomer, compared to 8 or 25 kDa. It can also bind and inhibit several Cys proteases (e.g., papain) simultaneously, and the term multicystatin thus refers to its multiple inhibitory domains (read more DOI: 10.1105/tpc.108.064717 and doi: 10.1105/tpc.108.064717)

2r73: Creativity in the SHOP

In moments of boredom or concern, seeing how beautiful the structures of nature are can reassure and inspire! I went back to my favourite molecules and selected some protein structures to bring some dynamism and creativity in our SHOP. Have a look at the NEW items with this protein!

This crystal structure belongs to the Possum Milk Whey Lipocalin Trichosurin such a lovely animal, right?

https://www.rcsb.org/structure/2r73
  • PubMed Abstract: 

Lipocalins are extracellular proteins (17-25 kDa) that bind and transport small lipophilic molecules. Trichosurin, a protein from the milk whey of the common brushtail possum (read more DOI: 10.1042/BJ20070567 or PMC2049081/)

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Brushtail possum

Open for submission

I am so happy you are snooping in the blog! Are you also writing some short poems and fascinated by science?

How about submitting your work to POETRY FROM THE LAB? Just click below or follow this link for further info.

1uz2: Creativity in the SHOP

In moments of boredom or concern, seeing how beautiful the structures of nature are can reassure and inspire! I went back to my favourite molecules and selected some protein structures to bring some dynamism and creativity in our SHOP. Have a look at the NEW items with this protein!

This crystal structure belongs to the Beta-Lactoglobulin that is a protein we find in our cappuccino or mozzarella. Pretty-looking, right?

β-Lactoglobulin is the major whey protein of cow and sheep‘s milk (~3 g/l), and is also present in many other mammalian species; a notable exception being humans. no clear function has been identified for β-lactoglobulin, this despite its being the biggest part of the fractional composition of the globular proteins isolated from whey (read moreDOI: 10.1021/bi0362469 or Wikipedia)

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